Furness, Sebastian G.: search on Z-Library

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1

Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex

Liang, Yi-Lynn, Khoshouei, Maryam, Glukhova, Alisa, Furness, Sebastian G. B., Zhao, Peishen, Clydesdale, Lachlan, Koole, Cassandra, Truong, Tin T., Thal, David M., Lei, Saifei, Radjainia, Mazdak, Dane

Journal:

Year:

2018

Language:

english

File:

PDF, 11.58 MB

english, 2018

2

TrkB Agonist LM22A-4 Increases Oligodendroglial Populations During Myelin Repair in the Corpus Callosum

Nguyen, Huynh T. H., Wood, Rhiannon J., Prawdiuk, Alexa R., Furness, Sebastian G. B., Xiao, Junhua, Murray, Simon S., Fletcher, Jessica L.

Journal:

Frontiers in Molecular Neuroscience

Year:

2019

File:

PDF, 5.95 MB

2019

3

The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism

Wootten, Denise, Reynolds, Christopher A., Smith, Kevin J., Mobarec, Juan C., Koole, Cassandra, Savage, Emilia E., Pabreja, Kavita, Simms, John, Sridhar, Rohan, Furness, Sebastian G.B., Liu, Mengjie,

Journal:

Year:

2016

Language:

english

File:

PDF, 3.62 MB

english, 2016

4

Dopamine and ghrelin receptor coâexpression and interaction in the spinal defecation centers

Furness, John B., Pustovit, Ruslan V., Syder, Andrew J., Ringuet, Mitchell T., Yoo, Eun Ji, Fanjul, Andrea, Wykosky, Jill, Fothergill, Linda J., Whitfield, Emily A., Furness, Sebastian G. B.

Journal:

Neurogastroenterology & Motility

Year:

2020

File:

PDF, 1.65 MB

2020

5

The expression of calcitonin receptor detected in malignant cells of the brain tumour glioblastoma multiforme and functional properties in the cell line A172

Peter J Wookey, Catriona A McLean, Peter Hwang, Sebastian G B Furness, Sandy Nguyen, Angela Kourakis, David L Hare, Jeffrey V Rosenfeld

Journal:

Year:

2012

Language:

english

File:

PDF, 2.10 MB

english, 2012

6

Beyond mere markers

Sebastian George Barton Furness, Kelly McNagny

Journal:

Immunologic Research

Year:

2006

Language:

english

File:

PDF, 748 KB

english, 2006

7

Consequences of splice variation on Secretin family G protein-coupled receptor function

Sebastian GB Furness, Denise Wootten, Arthur Christopoulos, Patrick M Sexton

Journal:

British Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 2.46 MB

english, 2012

8

The nature of efficacy at G protein-coupled receptors

Zhao, Peishen, Furness, Sebastian G.B.

Journal:

Biochemical Pharmacology

Year:

2019

File:

PDF, 1.96 MB

2019

9

Deconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor

Pham, Vi, Zhu, Yue, Dal Maso, Emma, Reynolds, Christopher A., Deganutti, Giuseppe, Atanasio, Silvia, Hick, Caroline A., Yang, Dehua, Christopoulos, Arthur, Hay, Debbie L., Furness, Sebastian G. B., Wa

Journal:

ACS Pharmacology & Translational Science

Year:

2019

Language:

english

File:

PDF, 1.14 MB

english, 2019

10

Phase-plate cryo-EM structure of a class B GPCR–G-protein complex

Liang, Yi-Lynn, Khoshouei, Maryam, Radjainia, Mazdak, Zhang, Yan, Glukhova, Alisa, Tarrasch, Jeffrey, Thal, David M., Furness, Sebastian G. B., Christopoulos, George, Coudrat, Thomas, Danev, Radostin,

Journal:

Year:

2017

Language:

english

File:

PDF, 8.06 MB

english, 2017

11

Ligand-Dependent Modulation of G Protein Conformation Alters Drug Efficacy

Furness, Sebastian George Barton, Liang, Yi-Lynn, Nowell, Cameron James, Halls, Michelle Louise, Wookey, Peter John, Dal Maso, Emma, Inoue, Asuka, Christopoulos, Arthur, Wootten, Denise, Sexton, Patri

Journal:

Year:

2016

Language:

english

File:

PDF, 4.89 MB

english, 2016

12

Identification of N,Nɛ-dimethyl-lysine in the murine dioxin receptor using MALDI-TOF/TOF- and ESI-LTQ-Orbitrap-FT-MS

Keyur A. Dave, Brett R. Hamilton, Tristan P. Wallis, Sebastian G.B. Furness, Murray L. Whitelaw, Jeffrey J. Gorman

Journal:

International Journal of Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 931 KB

english, 2007

13

Evidence that activation of ghrelin receptors of autonomic preganglionic neurons stimulates autonomic outflows

Yasutake Shimizu, Anthony D. Shafton, Dorota M. Ferens, Sebastian Jungnickel, Billie Hunne, John B. Furness

Journal:

Autonomic Neuroscience

Year:

2007

Language:

english

File:

PDF, 67 KB

english, 2007

14

SAE Technical Paper Series [SAE International SAE World Congress & Exhibition - (APR. 14, 2008)] SAE Technical Paper Series - Lean and Environmentally Friendly Manufacturing – Minimum Quantity Lubrication (MQL) is a Key Technology for Driving the Paradigm Shift in Machining Operations

Stoll, Alexander, Sebastian, Amando Jose, Klosinski, Robert, Furness, Richard

Year:

2008

Language:

english

File:

PDF, 3.43 MB

english, 2008

15

Deconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor

Pham, Vi, Zhu, Yue, Dal Maso, Emma, Reynolds, Christopher A., Deganutti, Giuseppe, Atanasio, Silvia, Hick, Caroline A., Yang, Dehua, Christopoulos, Arthur, Hay, Debbie L., Furness, Sebastian G. B., Wa

Journal:

ACS Pharmacology & Translational Science

Year:

2019

File:

PDF, 1.14 MB

2019

16

Na+/H+ Exchanger Regulatory Factor-1 Is a Hematopoietic Ligand for a Subset of the CD34 Family of Stem Cell Surface Proteins

Poh C. Tan, Sebastian G.B. Furness, Helen Merkens, Shujun Lin, Marcia L. McCoy, Calvin D. Roskelley, Jürgen Kast, Kelly M. McNagny

Journal:

Year:

2006

Language:

english

File:

PDF, 1.18 MB

english, 2006

17

Structure of the adenosine-bound human adenosine A1 receptor–Gi complex

Draper-Joyce, Christopher J., Khoshouei, Maryam, Thal, David M., Liang, Yi-Lynn, Nguyen, Anh T. N., Furness, Sebastian G. B., Venugopal, Hariprasad, Baltos, Jo-Anne, Plitzko, Jürgen M., Danev, Radosti

Journal:

Year:

2018

Language:

english

File:

PDF, 15.50 MB

english, 2018

18

A simple method to generate stable cell lines for the analysis of transient protein-protein interactions

Savage, Emilia Elizabeth, Wootten, Denise, Christopoulos, Arthur, Sexton, Patrick Michael, Furness, Sebastian George Barton

Journal:

Year:

2013

Language:

english

File:

PDF, 947 KB

english, 2013

19

TrkB Agonist LM22A-4 Increases Oligodendroglial Populations During Myelin Repair in the Corpus Callosum

Nguyen, Huynh T. H., Wood, Rhiannon J., Prawdiuk, Alexa R., Furness, Sebastian G. B., Xiao, Junhua, Murray, Simon S., Fletcher, Jessica L.

Journal:

Frontiers in Molecular Neuroscience

Year:

2019

Language:

english

File:

PDF, 5.95 MB

english, 2019

20

Struktur und Aktivitäten von Arzneimittelkommissionen in Deutschland

Sebastian Harder, Petra Thürmann, Andrea Steioff, Studiengruppe „Pharmakoökonomie und rationale Arzneimitteltherapie” der Deutschen Gesellschaft für Klinische Pharmakologie und Therapie

Journal:

Medizinische Klinik - Intensivmedizin und Notfallmedizin

Year:

1998

Language:

german

File:

PDF, 831 KB

german, 1998

21

Effects of mibefradil and Ni2+ on rebound depolarization and spikes in myenteric neurons of the guinea pig ileum

Hayato Matsuyama, Trung V. Nguyen, Toshihiro Unno, Seiichi Komori, Michelle Thacker, Louise Pontell, Billie Hunne, Sebastian Jungnickel, Kulmira Nurgali, John B. Furness

Journal:

Autonomic Neuroscience

Year:

2007

Language:

english

File:

PDF, 61 KB

english, 2007

22

Structure and dynamics of the active Gs-coupled human secretin receptor

Dong, Maoqing, Deganutti, Giuseppe, Piper, Sarah J., Liang, Yi-Lynn, Khoshouei, Maryam, Belousoff, Matthew J., Harikumar, Kaleeckal G., Reynolds, Christopher A., Glukhova, Alisa, Furness, Sebastian G.

Journal:

Nature Communications

Year:

2020

File:

PDF, 4.59 MB

2020

23

Receptor Activity-Modifying Proteins Differentially Modulate the G Protein-Coupling Efficiency of Amylin Receptors

Morfis, Maria, Tilakaratne, Nanda, Furness, Sebastian G. B., Christopoulos, George, Werry, Tim D., Christopoulos, Arthur, Sexton, Patrick M.

Journal:

Year:

2008

Language:

english

File:

PDF, 544 KB

english, 2008

24

Recent advances in understanding GLP-1R (glucagon-like peptide-1 receptor) function

Koole, Cassandra, Pabreja, Kavita, Savage, Emilia E., Wootten, Denise, Furness, Sebastian G.B., Miller, Laurence J., Christopoulos, Arthur, Sexton, Patrick M.

Journal:

Biochemical Society Transactions

Year:

2013

Language:

english

File:

PDF, 468 KB

english, 2013

25

The pleiotropy of dioxin toxicity — Xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles

Sebastian G.B. Furness, Fiona Whelan

Journal:

Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 742 KB

english, 2009

26

Coding GPCR-G protein specificity

Furness, Sebastian GB, Sexton, Patrick M

Journal:

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

27

Design, synthesis and characterization of a fluorescently labeled functional analog of full-length human ghrelin

Liu, Mengjie, Whitfield, Emily A., Fothergill, Linda J., Furness, John B., Wade, John D., Furness, Sebastian G.B., Hossain, Mohammed Akhter

Journal:

Biochemical and Biophysical Research Communications

Year:

2020

File:

PDF, 860 KB

2020

28

[IEEE 2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom) - Munich, Germany (2016.9.14-2016.9.16)] 2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom) - Application of recommender system methods for therapy decision support

Graber, Felix, Malberg, Hagen, Zaunseder, Sebastian, Beckert, Stefanie, Kuster, Denise, Schmitt, Jochen, Klinik, Susanne Abraham, fur Dermatologie, Poliklinik

Year:

2016

Language:

english

File:

PDF, 212 KB

english, 2016

29

What determines the magnitude of cellular response for activation of G protein-coupled receptors?

Furness, Sebastian G. B., Wootten, Denise, Sexton, Patrick M.

Journal:

Year:

2017

Language:

english

File:

PDF, 543 KB

english, 2017

30

Conformational Transitions and the Activation of Heterotrimeric G Proteins by G Protein-Coupled Receptors

Draper-Joyce, Christopher, Furness, Sebastian George Barton

Journal:

ACS Pharmacology & Translational Science

Year:

2019

File:

PDF, 3.34 MB

2019

31

Dianthin-30 or gelonin versus monomethyl auristatin E, each configured with an anti-calcitonin receptor antibody, are differentially potent in vitro in high-grade glioma cell lines derived from glioblastoma

Gilabert-Oriol, Roger, Furness, Sebastian G. B., Stringer, Brett W., Weng, Alexander, Fuchs, Hendrik, Day, Bryan W., Kourakis, Angela, Boyd, Andrew W., Hare, David L., Thakur, Mayank, Johns, Terrance

Journal:

Cancer Immunology, Immunotherapy

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

32

The dioxin (aryl hydrocarbon) receptor as a model for adaptive responses of bHLH/PAS transcription factors

Sebastian G.B. Furness, Michael J. Lees, Murray L. Whitelaw

Journal:

Year:

2007

Language:

english

File:

PDF, 280 KB

english, 2007

33

Key interactions by conserved polar amino acids located at the transmembrane helical boundaries in Class B GPCRs modulate activation, effector specificity and biased signalling in the glucagon-like peptide-1 receptor

Wootten, Denise, Reynolds, Christopher A., Smith, Kevin J., Mobarec, Juan C, Furness, Sebastian G.B., Miller, Laurence J., Christopoulos, Arthur, Sexton, Patrick M.

Journal:

Biochemical Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

34

The nature of efficacy at G protein-coupled receptors

Zhao, Peishen, Furness, Sebastian G.B.

Journal:

Biochemical Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.96 MB

english, 2019

35

Binding of Isolectin IB4 to Neurons of the Mouse Enteric Nervous System

Michelle Thacker, Feng Lan Zhang, Sebastian R Jungnickel, John B Furness

Journal:

Journal of Molecular Histology

Year:

2006

Language:

english

File:

PDF, 510 KB

english, 2006

36

Characterisation of signalling and regulation of common calcitonin receptor splice variants and polymorphisms

Dal Maso, Emma, Just, Rasmus, Hick, Caroline, Christopoulos, Arthur, Sexton, Patrick M., Wootten, Denise, Furness, Sebastian G.B.

Journal:

Biochemical Pharmacology

Year:

2017

Language:

english

File:

PDF, 9.36 MB

english, 2017

37

Structure and Dynamics of Adrenomedullin Receptors AM 1 and AM 2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins

Liang, Yi-Lynn, Belousoff, Matthew J., Fletcher, Madeleine M., Zhang, Xin, Khoshouei, Maryam, Deganutti, Giuseppe, Koole, Cassandra, Furness, Sebastian G. B., Miller, Laurence J., Hay, Debbie L., Chri

Journal:

ACS Pharmacology & Translational Science

Year:

2020

Language:

english

File:

PDF, 6.34 MB

english, 2020

38

Expression and activity of the calcitonin receptor family in a sample of primary human high-grade gliomas

Ostrovskaya, Anna, Hick, Caroline, Hutchinson, Dana S., Stringer, Brett W., Wookey, Peter J., Wootten, Denise, Sexton, Patrick M., Furness, Sebastian G. B.

Journal:

Year:

2019

File:

PDF, 1.44 MB

2019

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